Clinical Trial

Cold Snare Versus Cold Forceps Polypectomy for Small Lesions

Study acronym: Cold-SNAPS
Not Yet Recruiting
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Summary
The goal of this clinical trial is to compare the efficacy and the safety of a new device for cold forceps polypectomy (CFP)- a special jumbo forceps- to cold snare polypectomy (CSP) for small colorectal lesions, without adding peri- or post-procedural risks to the patient. The main questions it aims to answer are: * Does the cold forceps guarantee a complete endoscopic resection rate? * How many adverse events could the jumbo forceps reduce in comparison to CSP? * Does the lesion retrieval rate increase? * Does the polypectomy duration decrease? Participants will be randomized to one or to the other group when a polypoid or non-polypoid lesion is identified. If multiple polyps are found in the same patient, they will be removed using the same polypectomy technique. If polypectomy cannot be performed using the indicated technique, a crossover will be done according to the best practice of care principles.
Trial Details
NCT Number NCT06970808
Lead Sponsor Azienda USL Modena
Conditions Colorectal Adenoma, Colorectal Lesions
Enrollment 312 participants
Start Date 2025-12
Primary Completion 2027-10 (estimated)
Study Completion 2027-12 (estimated)
Updated on ClinicalTrials.gov 2025-05-14