Ameliorated Pap Tests and Cervical Cancer Screening Participation

The Pap test plays a crucial role in the early detection of cervical cancer. A pilot single-center randomized controlled trial applied the peak-end concept and added a non-painful step at the end of Pap smear screening, aimed to reduce recalled pain. However, there is still no multicenter study investigating the effect of the modified Pap test on cervical cancer screening participation. The present project is the first multicenter randomized controlled trial to expand the current scope of the peak-end theory into Pap tests and cervical cancer screening participation by adding a non-painful step at the end of Pap smear screening. Our multidisciplinary team (NTUH Pap Study Group) aims to provide innovative, feasible, and low-cost strategies for cervical cancer screening participation.

NCT Number	NCT06968871
Lead Sponsor	National Taiwan University Hospital Collaborators: National Taiwan University Hospital Hsin-Chu Branch, National Taiwan University, National Taiwan University Hospital Beihu Branch, National Taiwan University Hospital, Yun-Lin Branch, National Science and Technology Council
Conditions	Cervical Cancer Screening, Cervical Cancer Screening Methods
Enrollment	248 participants
Start Date	2026-03-01
Primary Completion	2030-12-31 (estimated)
Study Completion	2032-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-03-03