Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT06966908 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Hospital-Based Management of Patients With Chronic Hepatitis B Virus Infection

StatusRecruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗

Record History

See every version on ClinicalTrials.gov ↗

  1. Primary completion date: Jan 15, 2026 to Jun 30, 2027v2 Show 10 more changesShow less
    • Primary endpoints: 1 to 2
    • Trial status: Enrolling by Invitation to Recruiting
    • Enrollment target: 16000 to 16300
    • Study completion date: Jan 15, 2026 to Dec 31, 2027
    • Interventions: Facilitate the referral of in-hospital chronic hepatitis B patients and provide treatment and follow-up in the infectious disease… to Assessment of patient-reported outcomes (PROs) in patients with chronic hepatitis B. (Other), Facilitate the referral of in-hospital…
    • Eligibility criteria expanded, about 140 words
    • Secondary endpoints: 2 to 4
    • Study description expanded, about 117 words
    • Site details revised at 3 of 3 sites
    • Study arms: 1 to 2
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Since 2022, the Third Affiliated Hospital of Sun Yat-sen University has initiated the "Hot Wave Project", a comprehensive hepatitis B infection prevention and management system encompassing patient education, screening, referral, treatment, and follow-up. In 2024, this system was expanded to the Sixth Affiliated Hospital and the Fifth Affiliated Hospital of Sun Yat-sen University, transitioning into a multicenter, hospital-based cohort study on hepatitis B management.The primary objective of this study is to increase the referral rate of HBsAg-positive patients in non-hepatology/non-infectious disease departments to 50%. The secondary objective is to improve the treatment rate of hepatitis B infected patients in non-hepatology/non-infectious disease departments, particularly focusing on the diagnosed but untreated (DBU) population. Furthermore, this study aims to analyze the cost-effectiveness and clinical benefits of in-hospital hepatitis B screening and management strategies.In 2025, a Patient-Reported Outcomes (PRO) sub-study was added to the project to evaluate the impact of antiviral therapy on the Health-Related Quality of Life among a cohort of treatment-naïve patients with chronic hepatitis B.
Trial Details
NCT Number NCT06966908
Lead Sponsor Third Affiliated Hospital, Sun Yat-Sen University
Conditions
(from sponsor)		 Chronic Hepatitis B
Related terms Hepatitis B, Chronic
Enrollment 16,300 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov