Investigation of the Interplay Between Local Oral Inflammation, Microbiota and Systemic Immune Responses.

This is a clinical research study designed to measure changes in inflammation and the oral microbiome during a phase of good oral hygiene and the absence of oral hygiene. The goal of the study is to investigate the interplay between local oral inflammation, microbiota and systemic immune responses.

NCT Number	NCT06966492
Lead Sponsor	Colgate Palmolive Collaborators: The University of Texas Health Science Center, Houston
Conditions	Gingival Inflammation
Enrollment	20 participants
Start Date	2026-06
Primary Completion	2027-06 (estimated)
Study Completion	2027-06 (estimated)
Updated on ClinicalTrials.gov	2026-05-26