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Multiprofen-CC to Reduce Pain in Hand Arthritis

Study acronym: MRP-HAND
StatusRecruiting
PhasePhase 3
Started
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Record History

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  1. Notable Sponsor changed: McMaster University to St. Joseph's Healthcare Hamiltonv3 Show 5 more changesShow less
    • Recruitment opened
    • Start date changed from estimate of Jan 1, 2026 to Mar 9, 2026
    • Secondary endpoints: 4 to 3
    • Site details revised
    • Collaborators shortened, about 7 words
  2. Notable Start date: Aug 1, 2025 to Jan 1, 2026v2
  3. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This clinical trial aims to find out if using 1 gram of Multiprofen-CC cream on the hands three times a day for 4 weeks can help reduce pain in adults with hand osteoarthritis, compared to a placebo (a cream with no active medicine). The research team will also look at how Multiprofen-CC affects hand function, opioid use, and how patients feel about their overall improvement. In addition, the research team will keep track of any side effects. Participants will: * Use both Multiprofen-CC and a placebo (a cream with no active medicine) during the study, in a random order. * Be asked to apply 1 gram of cream to their hands three times a day for 2 weeks, following the manufacturer's instructions. * Attend a visit before starting the study, after 2 weeks, and after 6 weeks. * Report any symptoms they experience during the study.
Trial Details
NCT Number NCT06966206
Lead Sponsor St. Joseph's Healthcare Hamilton
Conditions
(from sponsor)
Hand Osteoarthritis
Related terms Arthritis, Osteoarthritis
Enrollment 42 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov