Clinical Trial

A Study to Learn How Different Amounts of the Study Medicine Called PF-07999415 Are Tolerated and Act in the Body in Healthy Adults

Active, Not Recruiting Phase 1
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Summary
The purpose of this clinical study is to learn about the safety and effects of the study medicine (called PF-07999415) in healthy adult participants. This study is seeking volunteers aged 18 to 65 years old who do not have any major health issues. Some participants in this study will receive a single dose of PF-07999415 as a shot in the thigh, abdomen, or arm at the study clinic. Afterward, participants will stay in a hospital-like setting for 2 weeks, where they will be monitored for reactions to the study medicine. The study team will compare the experiences of people receiving PF-07999415 to those of the people who do not. This will help the study team decide if PF-07999415 is safe. Participants will take part in this study for 3 to 7 months. During this time, participants will stay at the healthcare facility for 2 weeks and then come back for study visits every 2-4 weeks until completing the study.
Protocol Amendment History 10 amendments
This ClinicalTrials.gov record has been amended 10 times since 2025-05-02; most recent amendment 2026-07-22.
Status change: Recruiting → Active, Not Recruiting 2026-03-18
Status change: Not Yet Recruiting → Recruiting 2025-06-27
Trial Details
NCT Number NCT06965465
Lead Sponsor Pfizer
Conditions Healthy
Enrollment 32 participants
Start Date 2025-06-20
Primary Completion 2026-08-21 (estimated)
Study Completion 2026-08-21 (estimated)
Updated on ClinicalTrials.gov 2026-07-23