Clinical Trial

Treatment of Transfusion-dependent Nonsevere Aplastic Anemia With Luspatercept: a Multicenter Prospective Clinical Study

Not Yet Recruiting
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Summary
The goal of this clinical trial is to learn whether Luspatercept alone or in combination with Deferasirox can promote hematopoietic function in patients with transfusion-dependent non-severe aplastic anemia, as well as to assess the safety and efficacy of this treatment approach. The main questions it aims to answer is: whether the combination therapy of Luspatercept and Deferasirox can improve hemoglobin levels in these patients. Participants will receive Luspatercept every 3 to 5 weeks based on hemoglobin response, undergo complete blood counts every 1 to 3 weeks, and receive other necessary evaluations as required.
Trial Details
NCT Number NCT06964971
Lead Sponsor The First Affiliated Hospital of Zhejiang Chinese Medical University
Conditions Transfusion-dependent Non-severe Aplastic Anemia
Enrollment 90 participants
Start Date 2025-05-20
Primary Completion 2027-05-20 (estimated)
Study Completion 2027-06-30 (estimated)
Updated on ClinicalTrials.gov 2025-05-11