Clinical Trial

Evaluate Efficacy and Safety of PA5108 Ocular Implants in Primary Open Angle Glaucoma or Ocular Hypertension

Active, Not Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
The goal of this clinical trial is to determine the dose of PA5108 Ocular Implant that is effective and safe for the reduction of intraocular pressure in adult patients with open-angle glaucoma or ocular hypertension, compared to the standard treatment therapy.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-04-30; most recent amendment 2026-07-06.
Status change: Recruiting → Active, Not Recruiting 2026-07-06
Status change: Not Yet Recruiting → Recruiting 2025-06-10
Trial Details
NCT Number NCT06964191
Lead Sponsor PolyActiva Pty Ltd
Collaborators: IUVO S.r.l.
Conditions Glaucoma, Open-Angle, Ocular Hypertension
Enrollment 75 participants
Start Date 2025-05-31
Primary Completion 2026-11-15 (estimated)
Study Completion 2026-11-15 (estimated)
Updated on ClinicalTrials.gov 2026-07-08