Clinical Trial

Longitudinal Screening for Financial Hardship to Improve Outcomes in Patients With Advanced Cancer

Study acronym: PROOF
Recruiting
View on ClinicalTrials.gov →
Summary
The study aims to determine whether monthly remote digital financial hardship screening among adults with advanced/metastatic cancer, undergoing outpatient systemic therapy with non-curative intent, improves patient-centered outcomes, including financial worry, health-related quality of life (HRQoL), symptom burden, patient-reported cancer treatment adherence, and exploratory outcomes of overall survival, patient-reported economic burden, patient-reported support received, patient-reported financial coping strategies, and health insurance literacy.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-04-30; most recent amendment 2026-05-08.
Status change: Not Yet Recruiting → Recruiting 2025-12-02
Trial Details
NCT Number NCT06963723
Lead Sponsor Alliance Foundation Trials, LLC.
Collaborators: Memorial Sloan Kettering Cancer Center
Conditions Advanced Cancer, Metastatic Cancer
Enrollment 1,000 participants
Start Date 2025-07-01
Primary Completion 2028-10-01 (estimated)
Study Completion 2029-04-01 (estimated)
Updated on ClinicalTrials.gov 2026-05-12