Glaucoma Laser Assessment of Stability and Sustainability

The GLASS Study is designed to help researchers learn whether repeating a non-invasive laser treatment called DSLT (Direct Selective Laser Trabeculoplasty) can better control eye pressure in patients with early-stage glaucoma or ocular hypertension. All participants will receive the laser treatment in both eyes. After three months, one eye will be randomly selected to receive a second treatment, while the other eye will serve as a comparison. The goal is to see whether two treatments work better than one at keeping eye pressure low without using daily eye drops. This study will help doctors decide the best way to use this laser treatment to manage glaucoma and delay the need for medication. Participants will be followed for one year to monitor safety, eye pressure, and the need for any additional treatments.

NCT Number	NCT06963684
Lead Sponsor	Twin Cities Eye Consultants Collaborators: Alcon Research
Conditions	Glaucoma
Enrollment	48 participants
Start Date	2025-06
Primary Completion	2027-06 (estimated)
Study Completion	2027-08 (estimated)
Updated on ClinicalTrials.gov	2025-05-14