Mitigating Toxic Impact: The Role of Coenzyme Q10 in Post-Exposure Protection

This research study is being conducted to see if coenzyme Q10 (a nutritional supplement) might help to prevent and/or alleviate symptoms and health consequences and help to improve quality of life and physical function in residents affected by the February 2023 East Palestine, Ohio train derailment. This is a pilot study that is not powered to achieve benefit but seek to examine effect size and variance to aid in power calculations for a potential future better powered study.

NCT Number	NCT06962657
Lead Sponsor	University of California, San Diego
Conditions	Toxicant Induced Chronic Multisymptom Illness and Associated Symptoms and Comorbidities
Enrollment	20 participants
Start Date	2026-05-15
Primary Completion	2028-10-01 (estimated)
Study Completion	2028-10-01 (estimated)
Updated on ClinicalTrials.gov	2026-05-01