Healthy Volunteers Study

The purpose of this study is to examine the role of the bacterial environments and metabolites in the early detection and prediction of ovarian cancer development. Vaginal swabs and stool samples will be collected from healthy volunteers, or those without a known ovarian cancer diagnosis or genetic ovarian cancer risk. These samples will be compared to samples from participants with increased cancer risk and ovarian cancer diagnoses.

NCT Number	NCT06962059
Lead Sponsor	Abramson Cancer Center at Penn Medicine
Conditions	Ovarian Cancer, Genetic Predisposition to Disease
Enrollment	50 participants
Start Date	2025-04-21
Primary Completion	2027-01-15 (estimated)
Study Completion	2027-05-25 (estimated)
Updated on ClinicalTrials.gov	2026-02-05