Clinical Trial

Post-Operative Biomarker-Guided Precision Medicine For Cardiovascular Risk Reduction

Recruiting Early Phase 1
View on ClinicalTrials.gov →
Summary
The goal of this pilot study is to assess enrollment feasibility of a randomized trial of direct oral anticoagulant and high-intensity statin therapy versus usual care in patients with Myocardial Injury after Noncardiac Surgery (MINS). The primary aims of this study are to assess feasibility, study drug adherence, and optimize study design (entry criteria, study endpoints, sample size calculation, site selection) and recruitment strategies for the future multicenter randomized clinical trial studying biomarker-based care in post-operative patients at elevated cardiovascular (CV) risk.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-05-06; most recent amendment 2026-03-31.
Status change: Not Yet Recruiting → Recruiting 2025-10-07
Trial Details
NCT Number NCT06961630
Lead Sponsor NYU Langone Health
Collaborators: National Heart, Lung, and Blood Institute (NHLBI)
Conditions Myocardial Injury After Noncardiac Surgery
Enrollment 50 participants
Start Date 2025-10-07
Primary Completion 2027-03-31 (estimated)
Study Completion 2027-03-31 (estimated)
Updated on ClinicalTrials.gov 2026-04-06