Clinical Trial

Zanubrutinib Combined With G-CVP in Previously Untreated FL

Recruiting Phase 2
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Summary
The goal of this clinical trial is to learn the efficacy and safety of zanubrutinib in combination with G-CVP in previously untreated follicular lymphoma patients The main questions it aims to answer are: (1) Efficacy and safety of patients receiving zanubrutinib, obinutuzumab combined with cyclophosphamide, vincristine, and prednisone (CVP) regimen. (2) The difference in efficacy of patients with different minimal residual disease (MRD) status after treatment. Participants will receive zanubrutinib combined with G-CVP, maintenance therapy will be determined by the MRD status after treatment.
Trial Details
NCT Number NCT06959732
Lead Sponsor Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Conditions Follicular Lymphoma ( FL)
Enrollment 40 participants
Start Date 2025-01-01
Primary Completion 2027-06-30 (estimated)
Study Completion 2027-12-31 (estimated)
Updated on ClinicalTrials.gov 2025-05-07