Clinical Trial

Perioperative Homocysteine and Postoperative Complications/All-Cause Mortality in Elderly Non-Cardiac Surgery Patients

Completed
View on ClinicalTrials.gov →
Summary
This study aims to explore the association between perioperative homocysteine (Hcy) levels and their pre-to-postoperative changes with postoperative complications and all-cause mortality in elderly patients undergoing non-cardiac surgery. Besides, the dynamic changes in Hcy levels may reflect metabolic shifts, highlighting their potential value in predicting adverse postoperative outcomes. These findings suggest that monitoring perioperative Hcy levels and their changes could help identify high-risk patients and inform postoperative management strategies.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-04-28; most recent amendment 2026-05-07.
Trial Details
NCT Number NCT06959446
Lead Sponsor Chinese PLA General Hospital
Conditions Elderly, Homocysteinemia, AKI - Acute Kidney Injury, Mortality, Postoperative
Enrollment 29,156 participants
Start Date 2014-01-01
Primary Completion 2023-12-31 (estimated)
Study Completion 2023-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-05-12