Efficacy Of Oral Dexamethasone Versus Parenteral Dexamethasone In The Management Of Mild To Moderate Croup

Croup (laryngotracheobronchitis) is a viral infection of the upper airway that causes throat swelling, leading to a barking cough, stridor, and hoarseness. It mainly affects children aged 6 months to 12 years, peaking at around 2 years. Most cases are mild and self-limiting. Emergency treatments include cool mist, nebulized epinephrine, and steroids. Steroid therapy, particularly dexamethasone (oral or intramuscular), is commonly used, with recent studies suggesting intramuscular dexamethasone may be more effective. However, most research has focused on hospitalized patients, and there is a lack of local data for mild cases. This study aims to address that gap and improve patient counseling and future research

NCT Number	NCT06959407
Lead Sponsor	Arooj Khan
Conditions	Laryngotracheobronchitis, Croup
Enrollment	200 participants
Start Date	2024-10-01
Primary Completion	2025-03-01 (estimated)
Study Completion	2025-03-01 (estimated)
Updated on ClinicalTrials.gov	2026-01-29