Resistance Exercise Training on Vascular and Physical Function in Postmenopausal Women

Postmenopausal women often face risks of vascular dysfunction and muscle deterioration due to estrogen deficiency. These changes significantly increase the risk of cardiovascular disease and mortality. Previous studies have shown a significant positive correlation between vascular endothelial function and muscle strength. Moreover, muscle strength is a stronger predictor of mortality than muscle mass and is closely associated with the maintenance of functional independence in daily life. However, studies investigating the effects of whole-body progressive resistance training on vascular function and physical performance in postmenopausal women remain limited. This study aims to examine changes in vascular function and muscle strength in postmenopausal women following a whole-body progressive resistance training program.

NCT Number	NCT06958965
Lead Sponsor	National Yang Ming Chiao Tung University
Conditions	Postmenopausal Women
Enrollment	32 participants
Start Date	2025-06-09
Primary Completion	2025-11-03 (estimated)
Study Completion	2025-11-03 (estimated)
Updated on ClinicalTrials.gov	2026-03-13