Prophylactic Negative Pressure Wound Therapy in Laparotomy Wounds: A Randomized Clinical Trial

Total 70 participants meeting selection criteria will be enrolled in the study from operational theatre. They will be randomly divided in two groups by using lottery method. In group A, Negative Pressure Wound Therapy will be applied at end of procedure. In group B, no Negative Pressure Wound Therapy will be placed. They will be shifted to post-surgical wad for 72 hours and then will be discharged with prescription of standard antibiotics and will be followed-up in OPD for 30 days. If patient will develop surgical site wound infection, then it will be noted. If infection will not be cured with antibiotics course, then re-operation will be done. Patients complications will be managed as per hospital protocol. All this information will be recorded in proforma.

NCT Number	NCT06957964
Lead Sponsor	Dr Hamail Khanum
Conditions	Wound, Infection Prevention, Negative Pressure Wound Therapy
Enrollment	70 participants
Start Date	2025-03-25
Primary Completion	2025-06-25 (estimated)
Study Completion	2025-06-25 (estimated)
Updated on ClinicalTrials.gov	2025-05-06