Remote Mental Practice for Freezing of Gait in Parkinson's Disease

This single-blind, randomized controlled trial investigates the effects of a remotely delivered intervention based on mental practice (MP) combined with physical practice (PP) on freezing of gait (FOG) severity in people with idiopathic Parkinson's disease (PD). Fifty participants will be randomly assigned to either the experimental group (MP + PP) or a control group (PP + stretching). The intervention consists of 10 video-supervised sessions over 6 weeks. Primary outcomes include the Rapid Turn Test and percentage of time spent with FOG (%FOG). Secondary outcomes include the New Freezing of Gait Questionnaire (NFOG-Q), Movement Disorders Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS), Parkinson's Disease Questionnaire-39 (PDQ-39), and Telephone Montreal Cognitive Assessment (T-MoCA). The study aims to demonstrate whether MP using Dynamic Neuro-Cognitive Imagery (DNI) techniques can effectively reduce FOG severity and improve motor and cognitive function in people with PD.

NCT Number	NCT06957405
Lead Sponsor	University of Sao Paulo General Hospital
Conditions	Parkinson Disease, Freezing of Gait
Enrollment	50 participants
Start Date	2025-01-25
Primary Completion	2025-08 (estimated)
Study Completion	2028-01 (estimated)
Updated on ClinicalTrials.gov	2025-08-27