Clinical Comparison of Xenograft With Hydrogel Versus Xenograft Alone in the Socket Preservation After Tooth Extraction: A Randomized Controlled Clinical Trial

Clinical Comparison of xenograft with hydrogel versus xenograft alone in the socket preservation After tooth extraction: A Randomized controlled Clinical Trial The ideal scaffolds used for alveolar ridge preservation are supposed to show good biocompatibility, mechanical properties, and formability for irregularly shaped bone defects, as well as degradation rates matching bone growth . One of the most used synthetic scaffolds is hydrogel. Hydrogels owning three-dimensional cross-linked network structures have physical and chemical properties like human tissues . They can not only simulate the extracellular matrix (ECM) of bone but also allow the storage, and transport of various growth factors, cytokines, and nutrients due to their high permeability .

NCT Number	NCT06957197
Lead Sponsor	Cairo University
Conditions	Socket Perservation
Enrollment	26 participants
Start Date	2025-09-22
Primary Completion	2026-07-20 (estimated)
Study Completion	2026-08-20 (estimated)
Updated on ClinicalTrials.gov	2025-05-04