Clinical Trial

3D MRE-Based Evaluation of Meningioma Mechanical Properties and Histological Features

Recruiting
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Summary
This prospective single-center study aims to evaluate the feasibility and clinical utility of three-dimensional magnetic resonance elastography (3D MRE) in assessing tumor stiffness and adhesion in patients with meningioma undergoing surgical resection. By correlating preoperative MRE-derived stiffness and adhesion maps with intraoperative findings and histopathological features, the study seeks to determine whether MRE can serve as a noninvasive imaging biomarker for surgical planning, risk stratification, and prediction of tumor behavior.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-04-24.
Trial Details
NCT Number NCT06955208
Lead Sponsor Shengjing Hospital
Conditions Meningioma
Enrollment 300 participants
Start Date 2022-10-19
Primary Completion 2026-10-09 (estimated)
Study Completion 2027-10-09 (estimated)
Updated on ClinicalTrials.gov 2026-02-12