A Study on the Peripheral Blood in Patients With Acute Coronary Syndrome

The goal of this study is to conduct analyses the changes of cell growth factors, inflammatory factors, metabolites, plasma proteome, etc. in the blood of patients with ACS (acute coronary syndrome), as well as their correlations with the disease prognosis, based on multi-omics or other related research methods. The main questions it aims to answer are: The growth factors that have significant changes in the peripheral blood of the ACS population, especially fibroblast growth factors? Inflammatory factors and chemokines related to the onset of ACS? The metabolites and proteins that are significantly altered in the peripheral blood after the onset of ACS? Researchers will compare ACS population to CCS (Chronic Coronary Syndrome) population, and control group (patients without coronary artery stenosis, valvular heart disease, structural heart disease, or any other kind of cardiomyopathy).The peripheral venous blood from the participants will be collected within 24 hours after their admission to the hospital.

NCT Number	NCT06955143
Lead Sponsor	Second Affiliated Hospital of Wenzhou Medical University Collaborators: The Central Hospital of Lishui City
Conditions	Acute Coronary Syndrome, Chronic Coronary Syndrome
Enrollment	310 participants
Start Date	2025-03-11
Primary Completion	2025-08 (estimated)
Study Completion	2025-12 (estimated)
Updated on ClinicalTrials.gov	2025-07-25