Eligibility criteria+209 characters
Inclusion Criteria:
1)Age ≥ 18 years old;
2)Acute ischemic stroke symptom onset between 24 to 72 hours p [...] essed stroke, onset time refers to 'last-seen normal time';
3)Pre-stroke modified Rankin scale (mRS) score ≤1;
4)Baseline National Institutes of Health Stroke Scale (NIHSS) 6-25 (both inclusive) or a score of 4 or 5 with a disabling deficit (e.g., hemianopia, aphasia, and loss of hand function);
5)Neuroimaging:
Middle cerebral artery M1-M4 occlusion, ACA, PCA or M2basilar artery occlusion confirmed by CTA/MRA, middle cerebral artery M1 or M2 being responsible for signs and symptoms of acute [...] [...]
Secondary endpoints8 entries, revised
improvement on reperfusion at 24h after randomization (anterior circulation)
Study description+112 characters
Adult acute ischemic stroke patients due to large vessel occlusion (Middlemiddle cerebral artery M1-M4 occlusion, ACA, PCA or M2basilar artery occlusion confirmed by CTA/MRA) with baseline National Institutes of Health Stroke Scale (NIHSS) 6-25 or a score of 4 or 5 with a disabling deficit (e.g., hemianopia, aphasia, and loss of hand function) will be enrolled in this trial.
We use perfusion imaging to [...] CTP or MRI+PWI (ischemic core volume <70mL, mismatch ratio ≥>1.82, and mismatch volume ≥15mL>10 mL).
We will randomly assign patients who have salvageable bra [...]