WATERinMOTION Aquatic Therapy in Obese Men With Knee Osteoarthritis

This RCT evaluates whether WATERinMOTION aquatic therapy improves pain, function, and quality of life more effectively than land-based exercise in obese men with knee osteoarthritis (OA). We will assess clinical outcomes (WOMAC), serum biomarkers (COMP, IL-6), and real-world activity (accelerometry) at baseline, 8 weeks, and 6 months.

NCT Number	NCT06946329
Lead Sponsor	University of Sistan and Baluchestan
Conditions	Osteoarthritis, Knee, Obesity
Enrollment	100 participants
Start Date	2024-03-01
Primary Completion	2024-09-30 (estimated)
Study Completion	2025-05-01 (estimated)
Updated on ClinicalTrials.gov	2025-04-27