Treatment of Desmoid Fibromatosis With Arterial Embolization

Desmoid fibromatoses are rare and locally aggressive mesenchymal tumors. The current scientific evidence regarding the efficacy and safety of the treatment of desmoid fibromatosis by arterial embolization is constituted by several retrospective and prospective studies. These studies report promising results through the use of chemoembolization, that is, arterial embolization using particles loaded with chemotherapy. Instead, the type of treatment we propose would consist of injection of embolizing material without the use of chemotherapy, based on the positive results we have consistently reported over the years on arterial embolization of musculoskeletal tumors.

NCT Number	NCT06945887
Lead Sponsor	Istituto Ortopedico Rizzoli
Conditions	Desmoid Fibromatosis
Enrollment	20 participants
Start Date	2025-07-01
Primary Completion	2028-02 (estimated)
Study Completion	2029-02 (estimated)
Updated on ClinicalTrials.gov	2025-09-12