Clinical Trial

Improving Diagnostic Safety Through STeatosis Identification, Risk Stratification, and Referral in the ED

Study acronym: STIRRED
Enrolling by Invitation
View on ClinicalTrials.gov →
Summary
Hepatic steatosis is a common radiographic "incidental finding" that is overlooked and underreported to patients. The investigators developed a clinical decision support system using machine learning and natural language processing that will prompt reporting to patients and provide ED clinicians risk stratified follow-up care recommendations. Data on both the implementation and effectiveness of our intervention resulting from this trial will inform future use with a goal of ultimately improving diagnostic safety and outcomes for patients with hepatic steatosis.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-04-23; most recent amendment 2026-05-26.
Status change: Not Yet Recruiting → Enrolling by Invitation 2026-05-26
Trial Details
NCT Number NCT06944353
Lead Sponsor Northwestern University
Collaborators: Agency for Healthcare Research and Quality (AHRQ), University of Texas, Southwestern Medical Center at Dallas
Conditions Non-Alcoholic Fatty Liver Disease, Steatosis of Liver, Metabolic Dysfunction-Associated Steatotic Liver Disease
Enrollment 4,704 participants
Start Date 2025-12-04
Primary Completion 2027-01 (estimated)
Study Completion 2028-07 (estimated)
Updated on ClinicalTrials.gov 2026-05-29