This record was last updated January 27, 2026 (before its estimated May 2026 completion). Its status may not reflect the trial's current state.
Summary
The purpose of this study is to better understand oral wound healing in the aged participant following placement of platelet-rich fibrinogen (PRF). In this study, 12 participants requiring a posterior tooth extraction will be enroll: 6 participants aged 14-18, 6 participants aged 50-80. All will undergo a posterior tooth extraction with a small tissue specimen taken from the extraction site. Half of the participants will also have their blood drawn and platelet-rich fibrinogen placed in the extraction socket. Participants will return in 2 weeks for suture removal and another soft tissue sample. Participants will return at 3 months for a final post-operative radiograph. All soft tissue samples will undergo immunofluorescence.
Protocol Amendment History
2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-04-17; most recent amendment 2026-01-23.
Status change: Not Yet Recruiting → Recruiting2026-01-23