Comparison of Outcome of Open Appendectomy With and Without Transversus Abdominis Plane (TAP) Block

This study is being conducted to compare two types of pain management techniques in patients undergoing open appendectomy (surgical removal of the appendix through a traditional incision). One group of patients will receive a Transversus Abdominis Plane (TAP) block, a type of regional anesthesia given at the end of surgery to numb the abdominal area and reduce pain. The other group will undergo the same surgery without receiving the TAP block. The purpose of this study is to find out whether adding the TAP block helps in: Reducing postoperative pain Shortening the hospital stay Minimizing complications like nausea, vomiting, and delayed mobility Improving patient satisfaction after surgery Opioid medications are commonly used for pain control after surgery, but they come with side effects such as nausea, vomiting, dizziness, and risk of dependency. TAP block offers a promising alternative that may reduce or eliminate the need for opioids by targeting specific nerves in the abdominal wall. This will be a randomized controlled trial (considered the gold standard in medical research), meaning patients will be randomly assigned to one of the two groups to ensure fair comparison. The study will enroll 136 adult patients who are diagnosed with appendicitis and are scheduled for open appendectomy at Jinnah Hospital Lahore. By conducting this study, the researchers aim to provide strong scientific evidence on whether TAP block should be routinely used in appendectomy patients to enhance recovery and comfort. If proven effective, this could influence hospital protocols and improve post-surgery care both locally and internationally.

NCT Number	NCT06943456
Lead Sponsor	University of Health Sciences Lahore
Conditions	Appendicitis, Postoperative Pain
Enrollment	136 participants
Start Date	2025-05
Primary Completion	2026-05 (estimated)
Study Completion	2026-05 (estimated)
Updated on ClinicalTrials.gov	2025-04-29