Clinical Trial

Effects of Chlorhexidine Gluconate, Ozonated Water and Hypochlorous Acid Solutions Used in the Oral Care of Patients Supported by Mechanical Ventilation on the Integrity of the Oral Mucosa

Not Yet Recruiting Phase 4
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Record status
This record was last updated April 24, 2025 (before its estimated May 30, 2025 completion). Its status may not reflect the trial's current state.
Summary
The purpose of this clinical trial is to learn whether ozonated water and hypochlorous acid solution can restore the integrity of the oral mucosa. In addition, the investigators will learn about the safety of ozonated water and hypochlorous acid solution. The main questions that participants need to answer are: What medical conditions do participants have while taking ozonated water and hypochlorous acid solution? Investigators will compare ozonated water and hypochlorous acid solution with 0.12% chlorhexidine gluconate solution to see if it helps to restore the integrity of the oral mucosa. Participants: Participants will be asked to agree to receive oral care 4 times a day, every day for 1 week.
Trial Details
NCT Number NCT06942026
Lead Sponsor Aydin Adnan Menderes University
Conditions Oral Mucosal Disorder
Enrollment 63 participants
Start Date 2025-04-27
Primary Completion 2025-05-30 (estimated)
Study Completion 2025-09-30 (estimated)
Updated on ClinicalTrials.gov 2025-04-24