Chloride Imbalance in Preterm Infants

In adults and children low or high blood chloride levels are linked to the risk of death. The aim of this observational study is to determine whether there is a relationship between low or high blood chloride levels and the risk of death or long-term lung problems. We will also learn the risk factors and associated conditions of high or low blood chloride levels. We will include infants born before 32 weeks of pregnancy or have a birth weight of less than 1500 grams in the study. The main question it aims to answer is: Is there a relationship between low or high blood chloride levels in the first 4-6 weeks of life and risk of death or long-term lung problems in premature babies? We will examine the medical reports of babies who were followed up in neonatal intensive care unit over the past 5 years.

NCT Number	NCT06940856
Lead Sponsor	Kanuni Sultan Suleyman Training and Research Hospital
Conditions	Bronchopulmonary Dysplasia (BPD), Mortality Prediction, Chloride Disorder
Enrollment	500 participants
Start Date	2025-05-15
Primary Completion	2027-04-15 (estimated)
Study Completion	2027-12-15 (estimated)
Updated on ClinicalTrials.gov	2026-08-06