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Development of FAPI PET as a Non-invasive Biomarker of Pulmonary Fibrogenesis

StatusRecruiting
PhasePhase 2
Started
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Record History

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  1. Interventions: FAPI tracer (Drug), PET/MRI (Device) to FAPI tracer (Drug), PET/MRI (Device)
    • Eligibility criteria expanded, about 14 words
  2. Eligibility criteria expanded, about 124 wordsv9
  3. Trial status: Not Yet Recruiting to Recruiting
    • Start date changed from estimate of Dec 2025 to Nov 19, 2025
    • Site details revised
    v8
  4. Primary and study completion dates: Aug 2027 to Sep 2027
    • Start date: Nov 2025 to Dec 2025
    v7
  5. Start date: Sep 2025 to Nov 2025
    • Primary and study completion dates: Jun 2027 to Aug 2027
    v6
Show 4 earlier versionsHide 4 earlier versions
  1. Start date: Aug 2025 to Sep 2025v5
  2. Start date: Jul 2025 to Aug 2025v4
  3. Start date: Jun 2025 to Jul 2025v3
  4. Re-verified, no change to tracked fieldsv2
  1. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The goal of this clinical trial is to gain more information about how fibroblast activation protein inhibitor (FAPI) binds to a certain type of cells in fibrotic lung tissue and how this information can be used to better diagnose and track fibrotic lung disease activity. Participants will undergo up to 4 PET/MRI scans using the FAPI radiotracer.
Trial Details
NCT Number NCT06940427
Lead Sponsor University of Wisconsin, Madison
Conditions
(from sponsor)		 Fibrosis Lung
Related terms Pulmonary Fibrosis
Enrollment 50 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov