Clinical Trial

Topical Insulin for Ocular Surface Interface in Dry Eye Disease

Completed Phase 4
View on ClinicalTrials.gov →
Summary
This is a parallel randomized controlled trial for the treatment of dry eye disease. The main objective is to investigate the efficacy and safety of the use of insulin eye drops in the control of moderate-severe dry eye disease. Topical insulin drops will be compared to artificial tears in improving the ocular surface interface in patients with dry eye disease over 1 year period.
Protocol Amendment History 2 changes
critical Trial completed 2026-08-15
notable Primary completion pushed: 2026-01-20 -> 2026-04-19 2026-08-15
Trial Details
NCT Number NCT06939959
Lead Sponsor Khyber Teaching Hospital
Conditions Dry Eye, Insulin Sensitivity
Enrollment 128 participants
Start Date 2025-04-14
Primary Completion 2026-04-19 (estimated)
Study Completion 2026-04-25 (estimated)
Updated on ClinicalTrials.gov 2026-08-14