Clinical Trial

Dutch Registry of Pediatric Cardiac Arrest

Study acronym: PROGNOSE
Recruiting
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Summary
The goal of this observational study is to understand the long-term outcomes of children in the Netherlands who experience cardiac arrest, either in or outside of the hospital. The main questions it aims to answer are: What are the survival rates and neurological outcomes in children after cardiac arrest? What types of emergency and post-resuscitation care are provided, and how do they impact long-term recovery? How do children and their families function over time after the event? Researchers will analyze data from routine medical records and follow patients through standard outpatient visits. No extra procedures will be required beyond normal care. For those who survive to hospital discharge, additional follow-up data will be collected with consent. Participants will: Be children under 18 years old who have had a cardiac arrest and were treated in one of the seven participating academic hospitals Have their routine medical care data collected anonymously Be invited (if surviving) for follow-up visits at 3, 12, and 24 months post-arrest and at specific ages (5, 8, 12, and 17 years) to assess physical and psychological recovery
Trial Details
NCT Number NCT06938009
Lead Sponsor Matthijs de Hoog
Collaborators: Amsterdam UMC, Radboud University Medical Center, University Medical Center Groningen, Maastricht University Medical Center, UMC Utrecht, Zoll Medical Corporation, Stichting Vermeer14, Leiden University Medical Center
Conditions Cardiac Arrest (CA), Pediatric ALL
Enrollment 500 participants
Start Date 2023-06-14
Primary Completion 2030-01 (estimated)
Study Completion 2030-01 (estimated)
Updated on ClinicalTrials.gov 2025-04-22