Cortical Effects of Peripheral Proprioceptive Stimulation on the Motor Evoked Potentials of the Limbs

Through motor muscle potentials, we will observe how a peripheral somatosensory mechanical stimulus on key limb musculature communicates signals via afferent sensory fibers that encode proprioceptive signals from muscle spindles (particularly type Ia fibers) to the somatosensory cortex at rest, confirming the integrative hypothesis of movement. These results would support interventions aimed at addressing sensory deafferentation present in multiple health conditions related to movement disorders, where disuse or immobilization lead to changes in movement patterns and a decrease in neuronal activation in somatosensory cortex areas involved in constructing voluntary movement.

NCT Number	NCT06936579
Lead Sponsor	Facultat de ciencies de la Salut Universitat Ramon Llull
Conditions	Healthy Subjects
Enrollment	31 participants
Start Date	2025-05-20
Primary Completion	2025-07-15 (estimated)
Study Completion	2025-07-30 (estimated)
Updated on ClinicalTrials.gov	2025-04-24