Clinical Trial

Neoadjuvant Stereotactic Radiotherapy for Brain Metastasis

Study acronym: NeoSTROBE
Recruiting
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Summary
This multicentre proof-of-concept study, involving 4 centers, aims to establish the value of fractionated neoadjuvant stereotactic radiotherapy (NaSRT) as a new treatment paradigm for brain metastases (BM) in the frame of the Czech neurooncology network. Most relevant studies published to date used single-fraction radiotherapy and dealt with the inherent bias related to their retrospective nature. The researchers aim to increase the level of evidence for this treatment paradigm together with other similar ongoing studies.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-04-10.
Status change: Not Yet Recruiting → Recruiting 2025-05-01
Trial Details
NCT Number NCT06933199
Lead Sponsor University Hospital Ostrava
Collaborators: University Hospital Olomouc, Masaryk Memorial Cancer Institute, University Hospital Hradec Kralove
Conditions Brain Metastases
Enrollment 260 participants
Start Date 2025-05-01
Primary Completion 2028-12-31 (estimated)
Study Completion 2028-12-31 (estimated)
Updated on ClinicalTrials.gov 2025-05-04