Clinical Trial

The Therapeutic Effect of Curcumin in Nanogels Compared to 0.1% FAO in the Management of Oral Lichen Planus

Recruiting
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Record status
This record was last updated March 6, 2026 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
This randomized, double-blind clinical trial evaluates the therapeutic effects of curcumin in nanogels compared to 0.1% fluocinolone acetonide oral paste in the management of atrophic-erosive oral lichen planus (OLP). The study aims to determine whether curcumin nanogels, a natural treatment with enhanced bioavailability, are as effective and better tolerated than standard corticosteroid therapy.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-04-10; most recent amendment 2026-03-04.
Status change: Not Yet Recruiting → Recruiting 2026-03-04
Trial Details
NCT Number NCT06932848
Lead Sponsor Chulalongkorn University
Conditions Oral Lichen Planus
Enrollment 30 participants
Start Date 2025-06-01
Primary Completion 2026-06-30 (estimated)
Study Completion 2026-06-30 (estimated)
Updated on ClinicalTrials.gov 2026-03-06