Circumferential Pulmonary Vein Isolation Plus Transition Zone Modification in Atrial Fibrillation Patients Without Low-Voltage Areas

This study investigates two treatments for atrial fibrillation (AF) patients without low-voltage-areas (LVAs). It aims to determine whether adding transition zone modification (TZM) to the pulmonary vein isolation (PVI) improves long-term outcomes compared to PVI alone.

NCT Number	NCT06930599
Lead Sponsor	The First Affiliated Hospital with Nanjing Medical University
Conditions	Atrial Fibrillation (AF)
Enrollment	162 participants
Start Date	2025-04-09
Primary Completion	2026-10-09 (estimated)
Study Completion	2026-10-09 (estimated)
Updated on ClinicalTrials.gov	2025-04-16