Clinical Trial

RestoratIon of Myocardial Function by PeRcutaneous cOronary interVEntion in Patients With Ischemic CardioMyoPathy

Study acronym: IMPROVE-ICMP
Recruiting
View on ClinicalTrials.gov →
Summary
To compare the effects of physiology- and imaging-guided PCI combined with optimal medical therapy (OMT) versus OMT alone on the recovery of left ventricular systolic function in patients with ischemic cardiomyopathy and multivessel coronary artery disease.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-04-08; most recent amendment 2026-04-21.
Status change: Not Yet Recruiting → Recruiting 2025-06-23
Trial Details
NCT Number NCT06930092
Lead Sponsor Seoul National University Hospital
Collaborators: Seoul National University Bundang Hospital, Seoul National University Boramae Hospital
Conditions Ischemic Cardiomyopathy
Enrollment 158 participants
Start Date 2025-08-03
Primary Completion 2028-04-30 (estimated)
Study Completion 2029-04-30 (estimated)
Updated on ClinicalTrials.gov 2026-04-24