Effect of Bilateral SPG and Infraorbital Nerve Blocks on Recovery After Septorhinoplasty

This prospective, randomized, double-blind controlled study aims to compare the effects of bilateral sphenopalatine ganglion and infraorbital nerve blocks on postoperative recovery quality in patients undergoing elective septorhinoplasty under general anesthesia. A total of 90 adult patients (aged 18-65, ASA I-II) will be randomly assigned into two groups: Group 1 will receive bilateral sphenopalatine ganglion block, and Group 2 will receive bilateral infraorbital nerve block. Both blocks will be performed using 4 mL of 0.5% bupivacaine. The primary outcome is the quality of recovery assessed 24 hours after surgery using the QoR-15 questionnaire. Secondary outcomes include intraoperative anesthetic consumption (propofol, remifentanil), emergence agitation (RASS scale), postoperative pain (VAS), need for rescue analgesics (morphine), postoperative nausea and vomiting (VDS), antiemetic consumption (ondansetron), facial edema and hematoma, and length of stay in the post-anesthesia care unit (PACU). All procedures will follow standardized general anesthesia protocols. The study aims to determine which block technique provides superior postoperative recovery, better pain control, fewer side effects, and higher patient satisfaction. No placebo will be used, and no biological samples will be collected.

NCT Number	NCT06929429
Lead Sponsor	Konya City Hospital
Conditions	Quality of Recovery (QoR-15), Sphenopalatine Ganglion Block, Infraorbital Nerve Block
Enrollment	89 participants
Start Date	2025-06-19
Primary Completion	2026-04-29 (estimated)
Study Completion	2026-04-29 (estimated)
Updated on ClinicalTrials.gov	2026-05-06