The Effect of Controlled Hypotension

Controlled hypotension is currently used in spinal surgery to reduce bleeding at the surgical site, improve the surgeon's visibility, and decrease intraoperative blood loss. Although controlled hypotension is considered a beneficial method from a surgical perspective, it is important to be cautious about its side effects. One such side effect is cerebral perfusion insufficiency, which can be managed by monitoring cerebral circulation through regional cerebral oxygen saturation (rSO2). The aim of this study is to compare the effects of controlled hypotension at specific MAP ranges on cerebral oxygen saturation.

NCT Number	NCT06928870
Lead Sponsor	Ankara Etlik City Hospital
Conditions	Cerebral Hypoperfusion, Hypotension
Enrollment	60 participants
Start Date	2025-04-30
Primary Completion	2025-06-01 (estimated)
Study Completion	2025-06-30 (estimated)
Updated on ClinicalTrials.gov	2025-04-15