Non-invasive Vagus Nerve Stimulation and Sleep in Healthy Volunteers.

Participants will be chosen at random to receive a 30-minute stimulation of a specialized nerve (called a vagus nerve). The aim of this study is to determine whether a battery-operated portable device (current adjustable) attached to the outer ears (tragus) makes one more likely to improve on their sleep and quality of daily life. Participants will visit the lab on 2 occasions (one with a stimulating device and one without), 3 weeks apart for detailed instruction on setting up the ear stimulation and sleep kit in their home. Researchers will compare the sleep results from a PSG sleep device from the 2 sessions to determine the effect, if any on sleep.

NCT Number	NCT06928441
Lead Sponsor	University of Calgary Collaborators: Natural Sciences and Engineering Research Council, Canada
Conditions	Sleep
Enrollment	50 participants
Start Date	2025-04-30
Primary Completion	2029-04-30 (estimated)
Study Completion	2029-04-30 (estimated)
Updated on ClinicalTrials.gov	2025-04-15