Heat thErapy And mobiLity in COVID-19 Survivors

Post-acute sequelae of SARS-CoV-2 infection (PASC) is becoming a major risk factor for chronic diseases, with older adults and those with underlying health conditions at risk of developing persistent mobility limitations and disabilities. Although exercise intervention is a common strategy to restore functional capacity, it may not be feasible or enticing to many people with PASC. This clinical trial seeks to establish the tolerability and efficacy of at home lower-body heat therapy for improving functional capacity along with metabolic and vascular health in late-middle aged and older adults with PASC, also known as "long COVID".

NCT Number	NCT06928116
Lead Sponsor	University of Nebraska Collaborators: National Institute on Aging (NIA)
Conditions	Long COVID
Enrollment	99 participants
Start Date	2025-01-16
Primary Completion	2028-08-31 (estimated)
Study Completion	2029-08 (estimated)
Updated on ClinicalTrials.gov	2026-07-17