Risk Factors , Types and Neuroimaging Findings in Patients With Cerebral Palsy at Assiut University Children's Hospital

Cerebral palsy (CP) is the most common motor disorder among children as its worldwide prevalence is ranging from 1.5 to more than 4 per 1000 live births or children of a defined age range. * Pediatric cerebral palsy is a clinical syndrome caused by brain injury or lesions in children from before birth to 1 month after birth, and mainly manifests as non progressive central dyskinesia and abnormal posture. * Research has shown that the prevalence of cerebral palsy in children worldwide is about 3.16% , and results in heavy familial and social burdens as well as usage of medical resources, Despite considerable research , the complex etiology and pathogenesis of cerebral palsy remain unclear. The high-risk factors of cerebral palsy are complex and diverse (CP) appeared to be more prevalent in low- or middle-income countries than in high-income countries. (CP) prevalence was about 3.6 and 2.9 per 1000 children in Uganda and Egypt, respectively, but the prevalence was 1.8 to 2.3 cases per 1000 children in the USA, Europe, and Australia. -Cerebral palsy (CP) describes a group of disorders of the development of movement and posture, causing activity limitation, that are attributed to non-progressive disturbances that occurred in the developing fetal or infant brain. It begins in early childhood and persists through the lifespan. It was first reported as a movement disorder in the historical documents of the Sumerians, and Hippocrates. -Cerebral palsy (CP) is the major cause of motor impairment in young children, The clinical picture changes over time, and a recent review showed that referral for diagnosis typically happens between 10 and 21 months of age.

NCT Number	NCT06928012
Lead Sponsor	Assiut University
Conditions	Cerebral Palsy
Enrollment	60 participants
Start Date	2025-05-01
Primary Completion	2026-05-01 (estimated)
Study Completion	2026-06-01 (estimated)
Updated on ClinicalTrials.gov	2025-04-15