Clinical Trial

Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Type 2 Diabetes (ZUPREME 2)

Active, Not Recruiting Phase 2
View on ClinicalTrials.gov →
Record status
This record was last updated January 15, 2026 (before its estimated August 13, 2026 completion). Its status may not reflect the trial's current state.
Summary
The main purpose of this study is to investigate efficacy and safety of three doses of petrelintide versus placebo in participants with overweight or obesity and type 2 diabetes.
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2025-04-11; most recent amendment 2026-01-14.
Status change: Recruiting → Active, Not Recruiting 2025-12-09
Status change: Not Yet Recruiting → Recruiting 2025-05-15
Trial Details
NCT Number NCT06926842
Lead Sponsor Zealand Pharma
Collaborators: Parexel
Conditions Overweight, Type 2 Diabetes, Obesity
Enrollment 221 participants
Start Date 2025-04-22
Primary Completion 2026-08-13 (estimated)
Study Completion 2026-08-13 (estimated)
Updated on ClinicalTrials.gov 2026-01-15