Evaluation of Different Medicaments in the Management of Necrotic Primary Molars by Lesion Sterilization and Tissue Repair

Management of non-vital primary molars is challenging due to the natural anatomy of primary teeth, patients' young age, and their behavior toward dental treatment. A simple and effective technique such as Lesion Sterilization and Tissue Repair offers a solution to cases with poor prognosis; however, the medicaments used in this technique have some limitations. This study will evaluate three different medicaments regarding the clinical success, radiographic success, and antibacterial activity.

NCT Number	NCT06926322
Lead Sponsor	Ain Shams University
Conditions	Pain, Postoperative, Root Resorption, Persistent Infection, Necrotic Pulp
Enrollment	108 participants
Start Date	2025-10
Primary Completion	2027-08 (estimated)
Study Completion	2030-08 (estimated)
Updated on ClinicalTrials.gov	2025-10-02