Pregnancy Cohort Study: Pregnancy as a Window to Future Health

The goal of this observational cohort study is to gain deep insights into how metabolic disorders such as obesity or diabetes during pregnancy affect the metabolic and cardiovascular health of mother and child in the short and long term. It will investigate the following questions: * How do maternal metabolic disorders affect pregnancy outcomes? * How do maternal metabolic disorders affect fetal growth? * How do maternal metabolic disorders affect the newborn's metabolism and body composition? * How do maternal metabolic disorders during pregnancy affect breast milk composition? * How do maternal metabolic disorders during pregnancy affect the metabolic health of the mother after birth? Participants in this study are pregnant women who will be asked to come to the clinics for three visits during their pregnancy, as well as for the delivery of their baby, and one time 2-3 months thereafter. At each visit, researchers will perform physical examinations (such as body composition measurements) and collect biological samples (blood, urine, saliva), clinical information, and lifestyle data. At birth, researchers will collect cord blood and breast milk as well as clinical data of the delivery and the health of the baby. Researchers will measure body fat in newborn babies and at 2-3 months of age.

NCT Number	NCT06925815
Lead Sponsor	Medical University of Graz
Conditions	Healthy Pregnant Women, Obese Pregnant Women, Gestational Diabetes
Enrollment	800 participants
Start Date	2023-07-27
Primary Completion	2033-06 (estimated)
Study Completion	2034-06 (estimated)
Updated on ClinicalTrials.gov	2026-04-13