Study of Alloknesia in Atopic Dermatitis

Alloknesia is defined as pruritus (= itching) triggered by light mechanical stimuli, which are responsible for the perception of light touch under physiological conditions, but which are perceived as pruritic under pathological conditions. Alloknesia occurs mainly in the context of chronic pruritus. Consequently, patients suffering from chronic pruritus frequently perceive light touch sensations as pruritic, which can be particularly unpleasant and alter human interactions and quality of life on a daily basis. However, the epidemiology and burden of alloknesia have never been studied, whatever the cause of chronic pruritus.Atopic dermatitis is one of the main diseases causing chronic itching, and patients frequently complain of alloknesia. In this study, the investigators are studying the frequency of alloknesia in patients with atopic dermatitis and measuring the consequences of alloknesia in these patients.

NCT Number	NCT06923202
Lead Sponsor	University Hospital, Brest Collaborators: Almirall, S.A.
Conditions	Atopic Dermatosis, Alloknesie
Enrollment	160 participants
Start Date	2026-02-10
Primary Completion	2027-02-10 (estimated)
Study Completion	2027-02-10 (estimated)
Updated on ClinicalTrials.gov	2026-06-01