Clinical Trial

Between the Belly and the Brain: Distorted Gut-brain Crosstalk in Early-life Adversity

Study acronym: BellyBrain
Not Yet Recruiting
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Record status
This record was last updated April 10, 2025 (before its estimated April 2026 completion). Its status may not reflect the trial's current state.
Summary
The goal of this observational study is to learn about the effects of early-life adversity (ELA) on the composition of children's microbiome and on their psychosocial functioning. The main questions it aims to answer are: * Do children who have experienced ELA have lower gut microbial diversity and/or an altered gut microbial composition? * Do these microbiome alterations correlate with adverse neurodevelopmental outcomes, including increased levels of stress, social and/or affective problems?
Trial Details
NCT Number NCT06922773
Lead Sponsor Universitair Ziekenhuis Brussel
Conditions Early Life Adversity, Microbiome, Human, Anxiety Symptoms, Depressive Symptoms, Posttraumatic Stress Symptoms
Enrollment 50 participants
Start Date 2025-05
Primary Completion 2026-04 (estimated)
Study Completion 2026-06 (estimated)
Updated on ClinicalTrials.gov 2025-04-10