An important feature of neurosurgical anesthesia is early postoperative recovery of consciousness with minimal residual sedation. This is a key factor to enable early neurological assessment and early discovery of postoperative complications.
The goal of this single centre clinical trial is to compare propofol/remifentanil anesthesia delivered by manual total intravenous anesthesia (mTIVA) or target controlled infusion (TCI) for intracranial tumor resection via craniotomy. Anesthetic depth will be assessed by a simplified processed EEG (pEEG).
The main question is time spent within recommended pEEG- levels from anesthesia induction until end of surgery.
Secondary questions are:
* mean pEEG-level, time from end of surgery to consiousness,
* peroperative propofol/remifentanil consumption
* postoperative degree of sleepiness
* awareness assessment
Participants are adults having have planned surgery for open resection of a brain tumor and will receive general anesthesia with propofol and remifentanil randomized to mTIVA or TCI. pEEG vill be blinded.
* Participants will be asked to grade postoperative sleepiness using a specific scale
* Follow up regarding awareness will be performed.