HIPEC Surgery and Hemodynamics

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) involves the intraoperative administration of heated chemotherapeutic agents into the abdominal cavity following cytoreductive surgery (CRS). The increasing use of CRS combined with HIPEC has introduced certain procedural and physiological considerations that distinguish it from other surgical interventions, posing unique challenges for researchers and clinicians alike. Despite advancements in surgical and anesthetic techniques, this combined approach is frequently associated with significant hemodynamic instability, coagulation abnormalities, respiratory complications, and nutritional imbalances. The study aims to contribute to the existing body of knowledge by examining the physiological alterations induced by HIPEC, thereby offering practical insights and guidance for investigators involved in the management and study of this complex therapeutic modality.

NCT Number	NCT06922227
Lead Sponsor	Miray Gözde Özdemir
Conditions	Hemodynamics, Cytoreductive Surgery, Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
Enrollment	15 participants
Start Date	2025-04-01
Primary Completion	2025-07-01 (estimated)
Study Completion	2025-07-15 (estimated)
Updated on ClinicalTrials.gov	2025-04-13